Pathogenic
OpenCritic
Strong
OpenCritic Score
Score Distribution
"With that said, the Pathologic series has always demanded tolerance for a certain level of frustration because the payoff is so splendid, and in this regard, the third game is no exception. Intricately plotted and atmospheric, Pathologic 3’s great achievement is its reexamination of the series from a new perspective, with sweeping changes to the core that are as bold and ambitious as they are a totally natural extension of the new protagonist. It doesn’t match its predecessor’s level of tension, but in many ways it’s even more immersive and detailed. Not only does the Town-on-Gorkhon still make for one of the medium’s most transportive settings, but Daniil Dankovsky emerges as one of the medium’s richest protagonists."
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About
Pathogenic lets you play as a microscopic parasite waging war inside a host’s body. Use twin-stick controls to dodge immune cells and absorb resources to upgrade your organism. Each run is different as you mix organelles for new abilities, boost speed, release toxins, or fortify defenses. The goal is simple: survive waves of attacks while expanding your cellular territory across randomly generated maps. The game’s charm lies in its quirky biology-themed mechanics and tight roguelike loops. Procedural levels keep battles fresh, and the upgrade system encourages creative builds. Players praise the balance between action and strategy, with many noting the satisfaction of outsmarting the host’s defenses. Developed by Aberrant Labs and published by Slug Disco, it’s a bite-sized indie title that leans into its sci-fi premise without overcomplicating things.
Game Modes
Single player
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